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EXOSES LB+ has been created following the trend that seeks natural beauty through treatments that prevent and improve skin quality without the need to change the facial features.
EXOSES by Mediderma: the new generation of exosomes
Three specific solutions for different needs: Anti-aging (LA), Depigmenting (LW) and Revitalizing (LB+).
The most advanced and complete line of exosome therapy, formulated to offer comprehensive and personalized action for each treatment. Sterile systems that combine exosomes, liposomal lactoferrin, and bioactive complexes specifically developed to revitalize, rejuvenate, even skin tone, and slow hair loss.
We combine the most cutting-edge technologies to restore original vitality to the skin
Innovation in the development of exosomes
Know-how of the encapsulation of active ingredients in liposomes
BENEFITS OF EXOSOMES COMBINED WITH LACTOFERRIN
- Stimulates the synthesis of exosomes x4.
- Promotes greater collagen synthesis.
- Activates exosome expression markers CD9 and CD81.
- Increases intracellular calcium levels, which are directly related to an increase in exosome production.
- Liposomal lactoferrin increases the penetration rate and concentration by 1.5 times compared to free lactoferrin. It also increases its effectiveness and stability over time.
NO. OF EXOSOMES / CELL
362% increase in the number of exosomes cultured in a medium with lactoferrin compared to exosomes without lactoferrin.
Source: Kim J, You GE, Woo M, Chang NH, Lee J. Discovery of Lactoferrin as a Stimulant for hADSC-Derived EV Secretion and Proof of Enhancement of Resulting EVs through Skin Model. Int J Mol Sci. 2021;22(20):10993.
VIAL 1
It contains exosomes of the bacterium Lactobacillus brevis J2K-55 and liposomal lactoferrin.
Lactobacillus brevis J2K-55 is a patented microorganism obtained after fermentation of kimchi Dongchimi (water radish kimchi), a mixture of vegetables fermented in brine, on Jeju Island, Korea.
Size of exosomes: 30- 150nm.
Exosome concentration: 308 million particles/ml.
Different in vitro studies have been conducted with EXOSES LB VIAL 1 to evaluate its effects on human keratinocytes.
1. STRENGTHENS
Increases the expression of filaggrin, loricrin, and claudin-1 genes, involved in the correct functioning of the skin barrier function.
2. REGENERATES
Increases the viability and cellular proliferation of HaCaT keratinocytes.
3. CALMS
Reduces the expression of pro-inflammatory mediators (IL-6, IL-1β, TNF-α y COX-2), showing an anti-inflammatory effect.
EXOSES LA
A highly effective anti-aging treatment that targets the three pillars of skin aging: wrinkle formation, loss of firmness, and oxidative damage.
BENEFITS:
- • Reduces the depth of wrinkles and prevents their appearance.
- • Improves skin firmness and tone.
- • Improves skin texture, smoothness, and softness.
- • Protects against oxidative stress caused by free radicals and exposure to environmental factors.
EXOSES LW
Intensive depigmenting treatment that acts on all stages of the pigmentation process: from the initial skin triggers (inflammation) to melanin synthesis. Next-generation formula, with exosomes, tyrosinase inhibitors, melanin transfer modulators, and powerful antioxidants.
BENEFITS:
- • Softens and eliminates blemishes through different mechanisms of action.
- • Evens skin tone.
- • Prevents the appearance of blemishes by reducing oxidative damage.
- • Improves skin texture and radiance.
EXOSES LB+
A highly effective anti-aging treatment that targets the three pillars of skin aging: wrinkle formation, loss of firmness, and oxidative damage.
BENEFITS:
- • Reduces the depth of wrinkles and prevents their appearance.
- • Improves skin firmness and tone.
- • Improves skin texture, smoothness, and softness.
- • Protects against oxidative stress caused by free radicals and exposure to environmental factors.
EXOSES GF
Hair treatment that reduces hair loss and strengthens the hair follicle, helping to maintain a healthy scalp and thicker, stronger hair.
BENEFITS:
- • Reduces hair loss.
- • Stimulates hair growth and density.
- • Increases vascularization of the scalp, promoting oxygenation and nutrition of the follicles, resulting in stronger, healthier hair.
- • Improves hair quality, softness, and shine by retaining moisture and improving its structure.
COMING SOON
Vial 1 + Vial 2 / STERILE
VIAL 1 - REGENERATING
Lactobacillus brevis exosomes (LCTB)
Liposomal lactoferrin
VIAL 2 - VITALIZING
2 growth factors
2 types of hyaluronic acid
5 types of vitamins
11 amino acids
5 minerals
2 antioxidants
1 coenzyme
Polynucleotides
Cellular energizers
VIAL 2 - VITALIZING
- 2 growth factors
- 2 types of hyaluronic acid
- 5 types of vitamins
- 11 amino acids
- 5 minerals
- 2 antioxidants
- 1 coenzyme
- Cellular energizers
- 1 polynucleotide (PDRN)
Content
2x HYALURONIC ACID: 2 MOLECULAR WEIGHTS. Multi-level hydration
5 VITAMINS: VITAMIN A, B5, C, E and K. These nourish and moisturize the skin
11 AMINO ACIDS: ALANINE, ARGININE AC, ASPARTIC ACID, PHENYLALANINE, ISOLEUCINE, GLYCINE, HISTIDINE, PROLINE, SERINE, VALINE, AND THREONINE. These stimulate the synthesis of collagen
1 COENZYME: NAD. It accelerates cellular biochemical reactions
5 MINERALS: SILICON, ZINC, MAGNESIUM, SODIUM, AND CALCIUM. These accelerate cellular biochemical reactions
1 POLYNUCLEOTIDES: SODIUM DNA. It accelerates cellular biochemical reactions
2 ANTIOXIDANTS: THIOCTIC ACID, GLUTATHIONE. They protect cells from oxidative damage
1 CELLULAR ENERGIZER: ATP. It provides energy to cellular activities
2 GROWTH FACTORS: TIMP-2 and TGF-_2. Regenerating and rejuvenating